GLOW (BPC-157 + TB-500 + GHK-Cu)
Why this combination
GLOW extends the Wolverine repair pairing with GHK-Cu, a copper-binding tripeptide associated with collagen synthesis, skin remodeling, and wound cosmesis. The idea is to combine systemic/structural repair (BPC-157 + TB-500) with a skin- and collagen-oriented signal (GHK-Cu).
It is popular in 'recomp and recovery' contexts where users want both tissue repair and skin/appearance benefits. As with all repair stacks, the supporting data are preclinical and anecdotal, not from controlled human trials.
Per-compound dosing
| Compound | Dose | Frequency | Notes |
|---|---|---|---|
| BPC-157 | 250–500 mcg | 1–2× daily | — |
| TB-500 | 2–2.5 mg | 2× weekly then weekly | — |
| GHK-Cu | 1–2 mg | Daily (SC) or topical | Injectable GHK-Cu can sting; many use it topically for skin. |
Reconstitution math
For educational and research reference only. Not intended for human consumption, not medical advice. Compounds discussed are sold and used for laboratory research purposes only.
Separate vials
BPC-157 — 5 mg + 2 mL → 2,500 mcg/mL; 250 mcg = 0.1 mL (10 units).
TB-500 — 10 mg + 2 mL → 5,000 mcg/mL; 2,500 mcg = 0.5 mL (50 units).
GHK-Cu — 50 mg + 5 mL → 10,000 mcg/mL; 2,000 mcg = 0.2 mL (20 units). (GHK-Cu vials are commonly larger, e.g. 50 mg.)
Pre-blended (single vial)
Combining all three is possible but GHK-Cu's larger mass complicates a single vial. A common approach blends BPC-157 5 mg + TB-500 10 mg in one vial (3 mL → 0.3 mL delivers 500/1,000 mcg) and keeps GHK-Cu separate.
If you do blend GHK-Cu in, scale the water to keep each draw inside your syringe and recompute every concentration with the calculator before dosing.
Verify any blend with the reconstitution calculator before dosing — concentrations change for every compound when you alter the water volume.
Cycle length & alternatives
- Cycle length
- 4–8 week recovery block; GHK-Cu often continued topically beyond the injectable phase.
- Compared to alternatives
- GLOW = Wolverine + GHK-Cu (adds skin/collagen angle). KLOW adds KPV on top for an anti-inflammatory/gut component.
Sources & references
- [1]Pickart L, Margolina A. Regenerative and Protective Actions of the GHK-Cu Peptide. Int J Mol Sci 2018. ↗ source
Frequently asked questions
Should GHK-Cu be injected or used topically?
Both are used. Injectable GHK-Cu can cause stinging and the copper color is noticeable; many users apply it topically for skin-focused goals and reserve injections for BPC-157/TB-500.
For educational and research reference only. Not intended for human consumption, not medical advice. Compounds discussed are sold and used for laboratory research purposes only.
Related stacks
Wolverine (BPC-157 + TB-500)
The 'Wolverine' stack pairs two of the most widely discussed repair peptides because their proposed mechanisms are complementary rather than redundant. BPC-157 is associated with angiogenesis and localized tendon/ligament/gut signaling, while TB-500 (a synthetic fragment of thymosin beta-4) is associated with actin regulation and cell migration across tissue.
KLOW (KPV + BPC-157 + TB-500 + GHK-Cu)
KLOW adds KPV — a tripeptide fragment of alpha-MSH with anti-inflammatory properties — to the GLOW stack, aiming to pair tissue/skin repair with an inflammation- and gut-oriented signal.