KLOW (KPV + BPC-157 + TB-500 + GHK-Cu)
Why this combination
KLOW adds KPV — a tripeptide fragment of alpha-MSH with anti-inflammatory properties — to the GLOW stack, aiming to pair tissue/skin repair with an inflammation- and gut-oriented signal.
It is favored in protocols targeting recovery alongside gut or inflammatory complaints. The evidence base is preclinical and anecdotal across all four compounds.
Per-compound dosing
| Compound | Dose | Frequency | Notes |
|---|---|---|---|
| KPV | 200–500 mcg | 1–2× daily | — |
| BPC-157 | 250–500 mcg | 1–2× daily | — |
| TB-500 | 2–2.5 mg | 2× weekly then weekly | — |
| GHK-Cu | 1–2 mg | Daily (SC) or topical | — |
Reconstitution math
For educational and research reference only. Not intended for human consumption, not medical advice. Compounds discussed are sold and used for laboratory research purposes only.
Separate vials
KPV — 10 mg + 2 mL → 5,000 mcg/mL; 500 mcg = 0.1 mL (10 units); 250 mcg = 0.05 mL (5 units).
BPC-157, TB-500, GHK-Cu — as in the GLOW stack.
Pre-blended (single vial)
Four-way blends are awkward because of the differing masses. The cleaner approach runs KPV and GHK-Cu separately and blends only BPC-157 + TB-500.
Always recompute each compound's concentration in any shared vial with the calculator before drawing.
Verify any blend with the reconstitution calculator before dosing — concentrations change for every compound when you alter the water volume.
Cycle length & alternatives
- Cycle length
- 4–8 week recovery/anti-inflammatory block.
- Compared to alternatives
- KLOW = GLOW + KPV (adds an anti-inflammatory/gut component). For pure structural repair without the skin/gut angles, Wolverine is the minimal version.
Sources & references
- [1]Dalmasso G et al. KPV and intestinal inflammation (animal/cell). ↗ source
Frequently asked questions
What does KPV add to GLOW?
KPV is a fragment of alpha-MSH studied for anti-inflammatory effects, particularly in gut models. KLOW adds it for users whose goals include inflammation or gut-barrier support alongside repair.
For educational and research reference only. Not intended for human consumption, not medical advice. Compounds discussed are sold and used for laboratory research purposes only.
Related stacks
GLOW (BPC-157 + TB-500 + GHK-Cu)
GLOW extends the Wolverine repair pairing with GHK-Cu, a copper-binding tripeptide associated with collagen synthesis, skin remodeling, and wound cosmesis. The idea is to combine systemic/structural repair (BPC-157 + TB-500) with a skin- and collagen-oriented signal (GHK-Cu).
Wolverine (BPC-157 + TB-500)
The 'Wolverine' stack pairs two of the most widely discussed repair peptides because their proposed mechanisms are complementary rather than redundant. BPC-157 is associated with angiogenesis and localized tendon/ligament/gut signaling, while TB-500 (a synthetic fragment of thymosin beta-4) is associated with actin regulation and cell migration across tissue.